"thus"可以用於句首、句中、句末。當"thus"用於句首時，有無逗號隔開均可。例如，在句子"Most of the evidence was destroyed in the fire. Thus it would be almost impossible to prove him guilty."中，"thus"就用於句首，且沒有逗號隔開。又如，"We are not the owners of this building, therefore we cannot make major changes to it."中，"thus"也用於句首，同樣沒有逗號隔開。